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Melatonin enhances sensitivity to fluorouracil in oesophageal squamous cell carcinoma through inhibition of Erk and Akt pathway

Oesophageal squamous cell carcinoma (ESCC) is the sixth most common cause of cancer-associated death in the world and novel therapeutic alternatives are urgently warranted. In this study, we investigated the anti-tumour activity and underlying mechanisms of melatonin, an indoleamine compound secrete...

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Detalles Bibliográficos
Autores principales: Lu, Yun-Xin, Chen, Dong-Liang, Wang, De-Shen, Chen, Le-Zong, Mo, Hai-Yu, Sheng, Hui, Bai, Long, Wu, Qi-Nian, Yu, Hong-En, Xie, Dan, Yun, Jing-Ping, Zeng, Zhao-Lei, Wang, Feng, Ju, Huai-Qiang, Xu, Rui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133993/
https://www.ncbi.nlm.nih.gov/pubmed/27787516
http://dx.doi.org/10.1038/cddis.2016.330