CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5–AP-1 axis

Abnormal expression of cyclin-dependent kinase 5 (CDK5) has been found in several human cancers, whereas the role of CDK5 in the malignant development of colorectal cancer (CRC) has not been well characterized. Here we investigated the role of CDK5 in CRC and found that its expression was much highe...

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Detalles Bibliográficos
Autores principales: Zhuang, Kangmin, Zhang, Juchang, Xiong, Man, Wang, Xianfei, Luo, Xiaobei, Han, Lu, Meng, Yan, Zhang, Yali, Liao, Wenting, Liu, Side
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133995/
https://www.ncbi.nlm.nih.gov/pubmed/27735944
http://dx.doi.org/10.1038/cddis.2016.333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133995/
https://www.ncbi.nlm.nih.gov/pubmed/27735944
http://dx.doi.org/10.1038/cddis.2016.333

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