Cargando…
CDK5 functions as a tumor promoter in human colorectal cancer via modulating the ERK5–AP-1 axis
Abnormal expression of cyclin-dependent kinase 5 (CDK5) has been found in several human cancers, whereas the role of CDK5 in the malignant development of colorectal cancer (CRC) has not been well characterized. Here we investigated the role of CDK5 in CRC and found that its expression was much highe...
Autores principales: | Zhuang, Kangmin, Zhang, Juchang, Xiong, Man, Wang, Xianfei, Luo, Xiaobei, Han, Lu, Meng, Yan, Zhang, Yali, Liao, Wenting, Liu, Side |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133995/ https://www.ncbi.nlm.nih.gov/pubmed/27735944 http://dx.doi.org/10.1038/cddis.2016.333 |
Ejemplares similares
-
KIF20A promotes cellular malignant behavior and enhances resistance to chemotherapy in colorectal cancer through regulation of the JAK/STAT3 signaling pathway
por: Xiong, Man, et al.
Publicado: (2019) -
An Erk/Cdk5 axis controls the diabetogenic actions of PPARγ
por: Banks, Alexander S., et al.
Publicado: (2014) -
Comprehensive analysis of the prognosis and immune effect of the oncogenic protein Four Jointed Box 1
por: Huang, Mei, et al.
Publicado: (2023) -
Lipopolysaccharide-induced inflammation in human peritoneal mesothelial cells is controlled by ERK1/2-CDK5-PPARγ axis
por: Li, Zukai, et al.
Publicado: (2021) -
Pan-Cancer Analysis of the Oncogenic and Immunological Role of RCN3: A Potential Biomarker for Prognosis and Immunotherapy
por: Ding, Jian, et al.
Publicado: (2022)