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Desferrioxamine reduces ultrahigh-molecular-weight polyethylene-induced osteolysis by restraining inflammatory osteoclastogenesis via heme oxygenase-1

As wear particles-induced osteolysis still remains the leading cause of early implant loosening in endoprosthetic surgery, and promotion of osteoclastogenesis by wear particles has been confirmed to be responsible for osteolysis. Therapeutic agents targeting osteoclasts formation are considered for...

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Detalles Bibliográficos
Autores principales: Kang, Hui, Yan, Yufei, Jia, Peng, Yang, Kai, Guo, Changjun, Chen, Hao, Qi, Jin, Qian, Niandong, Xu, Xing, Wang, Fei, Li, Changwei, Guo, Lei, Deng, Lianfu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5133998/
https://www.ncbi.nlm.nih.gov/pubmed/27787522
http://dx.doi.org/10.1038/cddis.2016.339