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Block of both TGF-β and IL-2 signaling impedes Neurophilin-1(+) regulatory T cell and follicular regulatory T cell development
Understanding the mechanisms that lead to autoimmunity is critical for defining potential therapeutic pathways. In this regard there have been considerable efforts in investigating the interacting roles of TGF-β and IL-2 on the function regulatory T cells. We have taken advantage of dnTGF-βRII Il2ra...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134002/ https://www.ncbi.nlm.nih.gov/pubmed/27787514 http://dx.doi.org/10.1038/cddis.2016.348 |