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Block of both TGF-β and IL-2 signaling impedes Neurophilin-1(+) regulatory T cell and follicular regulatory T cell development

Understanding the mechanisms that lead to autoimmunity is critical for defining potential therapeutic pathways. In this regard there have been considerable efforts in investigating the interacting roles of TGF-β and IL-2 on the function regulatory T cells. We have taken advantage of dnTGF-βRII Il2ra...

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Detalles Bibliográficos
Autores principales: Li, Liang, Yang, Shu-Han, Yao, Yuan, Xie, Yu-Qing, Yang, Yan-Qing, Wang, Yin-Hu, Yin, Xue-Ying, Ma, Hong-Di, Gershwin, MEric, Lian, Zhe-Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134002/
https://www.ncbi.nlm.nih.gov/pubmed/27787514
http://dx.doi.org/10.1038/cddis.2016.348

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