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Alpha-mangostin from mangosteen (Garcinia mangostana Linn.) pericarp extract reduces high fat-diet induced hepatic steatosis in rats by regulating mitochondria function and apoptosis

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is caused by multiple factors including hepatic oxidative stress, lipotoxicity, and mitochondrial dysfunction. Obesity is among the risk factors for NAFLD alongside type 2 diabetes mellitus and hyperlipidemia. α- mangostin (α-MG) extracts from th...

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Detalles Bibliográficos
Autores principales: Tsai, Shin-Yu, Chung, Pei-Chin, Owaga, Eddy E., Tsai, I-Jong, Wang, Pei-Yuan, Tsai, Jeng-I, Yeh, Tien-Shun, Hsieh, Rong-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134003/
https://www.ncbi.nlm.nih.gov/pubmed/27980597
http://dx.doi.org/10.1186/s12986-016-0148-0