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Alpha-mangostin from mangosteen (Garcinia mangostana Linn.) pericarp extract reduces high fat-diet induced hepatic steatosis in rats by regulating mitochondria function and apoptosis
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD) is caused by multiple factors including hepatic oxidative stress, lipotoxicity, and mitochondrial dysfunction. Obesity is among the risk factors for NAFLD alongside type 2 diabetes mellitus and hyperlipidemia. α- mangostin (α-MG) extracts from th...
Autores principales: | Tsai, Shin-Yu, Chung, Pei-Chin, Owaga, Eddy E., Tsai, I-Jong, Wang, Pei-Yuan, Tsai, Jeng-I, Yeh, Tien-Shun, Hsieh, Rong-Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134003/ https://www.ncbi.nlm.nih.gov/pubmed/27980597 http://dx.doi.org/10.1186/s12986-016-0148-0 |
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