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Expression of insulin receptor (IR) A and B isoforms, IGF-IR, and IR/IGF-IR hybrid receptors in vascular smooth muscle cells and their role in cell migration in atherosclerosis

BACKGROUND: Abnormal proliferation and migration of vascular smooth muscle cells (VSMCs) is a major contributor to the development of atherosclerotic process. In a previous work, we demonstrated that the insulin receptor isoform A (IRA) and its association with the insulin-like growth factor-I recep...

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Detalles Bibliográficos
Autores principales: Beneit, N., Fernández-García, C. E., Martín-Ventura, J. L., Perdomo, L., Escribano, Ó., Michel, J. B., García-Gómez, G., Fernández, S., Díaz-Castroverde, S., Egido, J., Gómez-Hernández, A., Benito, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134076/
https://www.ncbi.nlm.nih.gov/pubmed/27905925
http://dx.doi.org/10.1186/s12933-016-0477-3