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Muscle PGC-1α modulates satellite cell number and proliferation by remodeling the stem cell niche

BACKGROUND: The myogenic capacity of satellite cells (SCs), adult muscle stem cells, is influenced by aging, exercise, and other factors. In skeletal muscle, the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a key regulator of oxidative metabolism and endurance training ada...

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Detalles Bibliográficos
Autores principales: Dinulovic, Ivana, Furrer, Regula, Beer, Markus, Ferry, Arnaud, Cardel, Bettina, Handschin, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134094/
https://www.ncbi.nlm.nih.gov/pubmed/27908291
http://dx.doi.org/10.1186/s13395-016-0111-9