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Muscle PGC-1α modulates satellite cell number and proliferation by remodeling the stem cell niche
BACKGROUND: The myogenic capacity of satellite cells (SCs), adult muscle stem cells, is influenced by aging, exercise, and other factors. In skeletal muscle, the peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) is a key regulator of oxidative metabolism and endurance training ada...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134094/ https://www.ncbi.nlm.nih.gov/pubmed/27908291 http://dx.doi.org/10.1186/s13395-016-0111-9 |