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Bile acid: a potential inducer of colon cancer stem cells

BACKGROUND: Although the unconjugated secondary bile acids, specifically deoxycholic acid (DCA) and lithocholic acid (LCA), are considered to be risk factors for colorectal cancer, the precise mechanism(s) by which they regulate carcinogenesis is poorly understood. We hypothesize that the cytotoxic...

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Detalles Bibliográficos
Autores principales: Farhana, Lulu, Nangia-Makker, Pratima, Arbit, Evan, Shango, Kathren, Sarkar, Sarah, Mahmud, Hamidah, Hadden, Timothy, Yu, Yingjie, Majumdar, Adhip P. N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134122/
https://www.ncbi.nlm.nih.gov/pubmed/27908290
http://dx.doi.org/10.1186/s13287-016-0439-4