Variable sensitivity to complement-dependent cytotoxicity in murine models of neuromyelitis optica

BACKGROUND: Studies of neuromyelitis optica (NMO), an autoimmune disease of the central nervous system (CNS), have demonstrated that autoantibodies against the water channel aquaporin-4 (AQP4) induce astrocyte damage through complement-dependent cytotoxicity (CDC). In developing experimental models...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Yiting, Harlow, Danielle E., Given, Katherine S., Owens, Gregory P., Macklin, Wendy B., Bennett, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134246/
https://www.ncbi.nlm.nih.gov/pubmed/27905992
http://dx.doi.org/10.1186/s12974-016-0767-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134246/
https://www.ncbi.nlm.nih.gov/pubmed/27905992
http://dx.doi.org/10.1186/s12974-016-0767-4

Ejemplares similares