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Systematic engineering of pentose phosphate pathway improves Escherichia coli succinate production

BACKGROUND: Succinate biosynthesis of Escherichia coli is reducing equivalent-dependent and the EMP pathway serves as the primary reducing equivalent source under anaerobic condition. Compared with EMP, pentose phosphate pathway (PPP) is reducing equivalent-conserving but suffers from low efficacy....

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Detalles Bibliográficos
Autores principales: Tan, Zaigao, Chen, Jing, Zhang, Xueli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134279/
https://www.ncbi.nlm.nih.gov/pubmed/27980672
http://dx.doi.org/10.1186/s13068-016-0675-y