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Hierarchical Bayesian inference for ion channel screening dose-response data
Dose-response (or ‘concentration-effect’) relationships commonly occur in biological and pharmacological systems and are well characterised by Hill curves. These curves are described by an equation with two parameters: the inhibitory concentration 50% (IC50); and the Hill coefficient. Typically just...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134333/ https://www.ncbi.nlm.nih.gov/pubmed/27918599 http://dx.doi.org/10.12688/wellcomeopenres.9945.2 |