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Exosomes derived from mature dendritic cells increase endothelial inflammation and atherosclerosis via membrane TNF‐α mediated NF‐κB pathway

Whether dendritic cell (DC) derived exosomes play a role in the progression of endothelial inflammation and atherosclerosis remains unclear. Using a transwell system and exosome release inhibitor GW4869, we demonstrated that mature DCs contributed to endothelial inflammation and exosomes were involv...

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Detalles Bibliográficos
Autores principales: Gao, Wei, Liu, Haibo, Yuan, Jie, Wu, Chaoneng, Huang, Dong, Ma, Yuanji, Zhu, Jianbing, Ma, Leilei, Guo, Junjie, Shi, Hongtao, Zou, Yunzeng, Ge, Junbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134386/
https://www.ncbi.nlm.nih.gov/pubmed/27515767
http://dx.doi.org/10.1111/jcmm.12923