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Class I HDACs specifically regulate E‐cadherin expression in human renal epithelial cells

Epithelial‐mesenchymal transition (EMT) and renal fibrosis are closely involved in chronic kidney disease. Inhibition of histone deacetylase (HDAC) has an anti‐fibrotic effect in various diseases. However, the pathophysiological role of isoform‐specific HDACs or class‐selective HDACs in renal fibros...

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Detalles Bibliográficos
Autores principales: Choi, Sin Y., Kee, Hae J., Kurz, Thomas, Hansen, Finn K., Ryu, Yuhee, Kim, Gwi R., Lin, Ming Q., Jin, Li, Piao, Zhe H., Jeong, Myung H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134402/
https://www.ncbi.nlm.nih.gov/pubmed/27420561
http://dx.doi.org/10.1111/jcmm.12919