Activation of liver X receptor attenuates lysophosphatidylcholine‐induced IL‐8 expression in endothelial cells via the NF‐κB pathway and SUMOylation

The liver X receptor (LXR) is a cholesterol‐sensing nuclear receptor that has an established function in lipid metabolism; however, its role in inflammation is elusive. In this study, we showed that the LXR agonist GW3965 exhibited potent anti‐inflammatory activity by suppressing the firm adhesion o...

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Detalles Bibliográficos
Autores principales: Bi, Xukun, Song, Jiale, Gao, Jing, Zhao, Juanjuan, Wang, Meihui, Scipione, Corey A., Koschinsky, Marlys L., Wang, Zhao V., Xu, Shiming, Fu, Guosheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134410/
https://www.ncbi.nlm.nih.gov/pubmed/27489081
http://dx.doi.org/10.1111/jcmm.12903

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134410/
https://www.ncbi.nlm.nih.gov/pubmed/27489081
http://dx.doi.org/10.1111/jcmm.12903

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