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Optimized Detection of Plasmodium falciparum Topoisomerase I Enzyme Activity in a Complex Biological Sample by the Use of Molecular Beacons

The so-called Rolling Circle Amplification allows for amplification of circular DNA structures in a manner that can be detected in real-time using nucleotide-based molecular beacons that unfold upon recognition of the DNA product, which is being produced during the amplification process. The unfoldi...

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Detalles Bibliográficos
Autores principales: Givskov, Asger, Kristoffersen, Emil L., Vandsø, Kamilla, Ho, Yi-Ping, Stougaard, Magnus, Knudsen, Birgitta R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134575/
https://www.ncbi.nlm.nih.gov/pubmed/27854277
http://dx.doi.org/10.3390/s16111916