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Optimized Detection of Plasmodium falciparum Topoisomerase I Enzyme Activity in a Complex Biological Sample by the Use of Molecular Beacons
The so-called Rolling Circle Amplification allows for amplification of circular DNA structures in a manner that can be detected in real-time using nucleotide-based molecular beacons that unfold upon recognition of the DNA product, which is being produced during the amplification process. The unfoldi...
Autores principales: | Givskov, Asger, Kristoffersen, Emil L., Vandsø, Kamilla, Ho, Yi-Ping, Stougaard, Magnus, Knudsen, Birgitta R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134575/ https://www.ncbi.nlm.nih.gov/pubmed/27854277 http://dx.doi.org/10.3390/s16111916 |
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