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Effects of Cyclin Dependent Kinase 9 inhibition on zebrafish larvae

CDK9 is a known regulator of cellular transcription, growth and proliferation. Small molecule inhibitors are currently being developed and assessed in clinical trials as anti-cancer drugs. The zebrafish embryo provides an ideal model to explore the effects of CDK9 inhibition in-vivo. This has not be...

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Detalles Bibliográficos
Autores principales: Matrone, Gianfranco, Mullins, John J., Tucker, Carl S., Denvir, Martin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134698/
https://www.ncbi.nlm.nih.gov/pubmed/27715402
http://dx.doi.org/10.1080/15384101.2016.1231283