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Critical influence of the thymus on peripheral T cell homeostasis

INTRODUCTION: A tight balance between regulatory CD4(+)Foxp3(+) (Treg) and conventional CD4(+)Foxp3(−) (Tconv) T cell subsets in the peripheral compartment, maintained stable throughout most of lifetime, is essential for preserving self‐tolerance along with efficient immune responses. An excess of T...

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Detalles Bibliográficos
Autores principales: Vianna, Pedro Henrique Oliveira, Canto, Fábio B., Nogueira, Jeane S., Nunes, Caroline Fraga Cabral Gomes, Bonomo, Adriana César, Fucs, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5134722/
https://www.ncbi.nlm.nih.gov/pubmed/27980781
http://dx.doi.org/10.1002/iid3.132