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Authorization of Animal Experiments Is Based on Confidence Rather than Evidence of Scientific Rigor

Accumulating evidence indicates high risk of bias in preclinical animal research, questioning the scientific validity and reproducibility of published research findings. Systematic reviews found low rates of reporting of measures against risks of bias in the published literature (e.g., randomization...

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Detalles Bibliográficos
Autores principales: Vogt, Lucile, Reichlin, Thomas S., Nathues, Christina, Würbel, Hanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135031/
https://www.ncbi.nlm.nih.gov/pubmed/27911892
http://dx.doi.org/10.1371/journal.pbio.2000598