Non-imidazole-based histamine H3 receptor antagonists with anticonvulsant activity in different seizure models in male adult rats

A series of twelve novel non-imidazole-based ligands (3–14) was developed and evaluated for its in vitro binding properties at the human histamine H3 receptor (hH3R). The novel ligands were investigated for their in vivo protective effects in different seizure models in male adult rats. Among the H3...

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Detalles Bibliográficos
Autores principales: Sadek, Bassem, Saad, Ali, Latacz, Gniewomir, Kuder, Kamil, Olejarz, Agnieszka, Karcz, Tadeusz, Stark, Holger, Kieć-Kononowicz, Katarzyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135077/
https://www.ncbi.nlm.nih.gov/pubmed/27932863
http://dx.doi.org/10.2147/DDDT.S116192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135077/
https://www.ncbi.nlm.nih.gov/pubmed/27932863
http://dx.doi.org/10.2147/DDDT.S116192

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