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SiRNA Targeting mTOR Effectively Prevents the Proliferation and Migration of Human Lens Epithelial Cells

Posterior capsule opacification (PCO) is the most common complication that causes visual decrease after extracapsular cataract surgery. The primary cause of PCO formation is the proliferation of the residual lens epithelial cells (LECs). The mammalian target of rapamycin (mTOR) plays an important ro...

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Detalles Bibliográficos
Autores principales: Zhang, Chunmei, Liu, Jingjing, Jin, Na, Zhang, Guiming, Xi, Yahui, Liu, Hongling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135089/
https://www.ncbi.nlm.nih.gov/pubmed/27911920
http://dx.doi.org/10.1371/journal.pone.0167349