Driving Cells to the Desired State in a Bimodal Distribution through Manipulation of Internal Noise with Biologically Practicable Approaches

The stochastic nature of gene regulatory networks described by Chemical Master Equation (CME) leads to the distribution of proteins. A deterministic bistability is usually reflected as a bimodal distribution in stochastic simulations. Within a certain range of the parameter space, a bistable system...

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Detalles Bibliográficos
Autores principales: Shu, Che-Chi, Yeh, Chen-Chao, Jhang, Wun-Sin, Lo, Shih-Chiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135133/
https://www.ncbi.nlm.nih.gov/pubmed/27911933
http://dx.doi.org/10.1371/journal.pone.0167563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135133/
https://www.ncbi.nlm.nih.gov/pubmed/27911933
http://dx.doi.org/10.1371/journal.pone.0167563

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