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The Yersinia pestis Effector YopM Inhibits Pyrin Inflammasome Activation

Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative bacteria, and secreted T3SS effectors can block key aspects of host cell signaling. To counter this, innate immune responses can also sense some T3SS components to initiate anti-bacterial mechanisms. Th...

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Detalles Bibliográficos
Autores principales: Ratner, Dmitry, Orning, M. Pontus A., Proulx, Megan K., Wang, Donghai, Gavrilin, Mikhail A., Wewers, Mark D., Alnemri, Emad S., Johnson, Peter F., Lee, Bettina, Mecsas, Joan, Kayagaki, Nobuhiko, Goguen, Jon D., Lien, Egil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135138/
https://www.ncbi.nlm.nih.gov/pubmed/27911947
http://dx.doi.org/10.1371/journal.ppat.1006035