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Receptor dimer stabilization by hierarchical plasma membrane microcompartments regulates cytokine signaling

The interaction dynamics of signaling complexes is emerging as a key determinant that regulates the specificity of cellular responses. We present a combined experimental and computational study that quantifies the consequences of plasma membrane microcompartmentalization for the dynamics of type I i...

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Detalles Bibliográficos
Autores principales: You, Changjiang, Marquez-Lago, Tatiana T., Richter, Christian Paolo, Wilmes, Stephan, Moraga, Ignacio, Garcia, K. Christopher, Leier, André, Piehler, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135388/
https://www.ncbi.nlm.nih.gov/pubmed/27957535
http://dx.doi.org/10.1126/sciadv.1600452