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PKR promotes choroidal neovascularization via upregulating the PI3K/Akt signaling pathway in VEGF expression

PURPOSE: The aim of this study was to investigate the functions of dsRNA-activated protein kinase (PKR) in choroidal neovascularization (CNV) and related signaling pathways in the production of vascular endothelial growth factor (VEGF). METHODS: A chemical hypoxia model of in vitro RF/6A cells, a rh...

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Detalles Bibliográficos
Autores principales: Zhu, Manhui, Liu, Xiaojuan, Wang, Shengcun, Miao, Jin, Wu, Liucheng, Yang, Xiaowei, Wang, Ying, Kang, Lihua, Li, Wendie, Cui, Chen, Chen, Hui, Sang, Aimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135740/
https://www.ncbi.nlm.nih.gov/pubmed/27994435