A genetic risk score composed of rheumatoid arthritis risk alleles, HLA-DRB1 haplotypes, and response to TNFi therapy – results from a Swedish cohort study

BACKGROUND: To prevent debilitating and irreversible joint damage, rheumatoid arthritis (RA) is often treated with tumor necrosis factor inhibitor (TNFi), but many patients do not respond to this costly therapy. Few predictors for response are known, and it has been proposed that genetic factors whi...

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Detalles Bibliográficos
Autores principales: Jiang, Xia, Askling, Johan, Saevarsdottir, Saedis, Padyukov, Leonid, Alfredsson, Lars, Viatte, Sebastien, Frisell, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135751/
https://www.ncbi.nlm.nih.gov/pubmed/27912794
http://dx.doi.org/10.1186/s13075-016-1174-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135751/
https://www.ncbi.nlm.nih.gov/pubmed/27912794
http://dx.doi.org/10.1186/s13075-016-1174-z

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