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A novel long non-coding RNA lnc-GNAT1-1 is low expressed in colorectal cancer and acts as a tumor suppressor through regulating RKIP-NF-κB-Snail circuit

BACKGROUND: The role of long non-coding RNAs (lncRNAs) in colorectal cancer (CRC) progression has not fully been elucidated. This study was designed to report the identification of a novel lncRNA, lnc-GNAT1-1, and its functional role in CRC progression. METHODS: lncRNA expression profile microarray...

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Detalles Bibliográficos
Autores principales: Ye, Chunxiang, Shen, Zhanlong, Wang, Bo, Li, Yansen, Li, Tao, Yang, Yang, Jiang, Kewei, Ye, Yingjiang, Wang, Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135755/
https://www.ncbi.nlm.nih.gov/pubmed/27912775
http://dx.doi.org/10.1186/s13046-016-0467-z