Cargando…

A novel long non-coding RNA lnc-GNAT1-1 is low expressed in colorectal cancer and acts as a tumor suppressor through regulating RKIP-NF-κB-Snail circuit

BACKGROUND: The role of long non-coding RNAs (lncRNAs) in colorectal cancer (CRC) progression has not fully been elucidated. This study was designed to report the identification of a novel lncRNA, lnc-GNAT1-1, and its functional role in CRC progression. METHODS: lncRNA expression profile microarray...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ye, Chunxiang, Shen, Zhanlong, Wang, Bo, Li, Yansen, Li, Tao, Yang, Yang, Jiang, Kewei, Ye, Yingjiang, Wang, Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135755/ https://www.ncbi.nlm.nih.gov/pubmed/27912775 http://dx.doi.org/10.1186/s13046-016-0467-z

Ejemplares similares

MicroRNA-4284 promotes gastric cancer tumorigenicity by targeting ten-eleven translocation 1
por: Li, Yansen, et al.
Publicado: (2018)

Lnc-HSD17B11-1:1 Functions as a Competing Endogenous RNA to Promote Colorectal Cancer Progression by Sponging miR-338-3p to Upregulate MACC1
por: Zhang, Wei, et al.
Publicado: (2020)

Tumor-associated macrophages regulate gastric cancer cell invasion and metastasis through TGFβ2/NF-κB/Kindlin-2 axis
por: Wang, Zhu, et al.
Publicado: (2020)

LncRNA XIST acts as a tumor suppressor in prostate cancer through sponging miR-23a to modulate RKIP expression
por: Du, Yang, et al.
Publicado: (2017)

Robust visual cortex evoked potentials (VEP) in Gnat1 and Gnat2 knockout mice
por: Flood, Michael D., et al.
Publicado: (2022)

The Gnat and the Camel
Publicado: (1891)

circ-ZEB1 regulates epithelial-mesenchymal transition and chemotherapy resistance of colorectal cancer through acting on miR-200c-5p
por: Chen, Hongyu, et al.
Publicado: (2022)

Straining at a Gnat
Publicado: (1893)

Straining at a Gnat
por: Francis, Chas. E.
Publicado: (1885)

The RAF Kinase Inhibitor Protein (RKIP): Good as Tumour Suppressor, Bad for the Heart
por: Abd Alla, Joshua, et al.
Publicado: (2022)

Characteristics of alpha-fetoprotein-positive gastric cancer revealed by analysis of cancer databases and transcriptome sequencing data
por: Li, Yansen, et al.
Publicado: (2023)

Young adults with colon cancer: clinical features and surgical outcomes
por: Wang, Chao, et al.
Publicado: (2023)

A Functional Network Model of the Metastasis Suppressor PEBP1/RKIP and Its Regulators in Breast Cancer Cells
por: Ahmed, Mahmoud, et al.
Publicado: (2021)

Cancer resistance via the downregulation of the tumor suppressors RKIP and PTEN expressions: therapeutic implications
por: Moghaddam, Matthew, et al.
Publicado: (2023)

Smaller than a gnat
Publicado: (2006)

A Handbook of Gnats or Mosquitos
Publicado: (1902)

Bacillus Lepræ, Gnats and Bugs
por: Goodhue, E. S.
Publicado: (1906)

A Handbook of the Gnats or Mosquitoes
Publicado: (1900)

Changes in Expression of Tumor Suppressor Gene RKIP Impact How Cancers Interact with Their Complex Environment
por: Figy, Christopher, et al.
Publicado: (2023)

Long Non-coding RNA lnc-GNAT1-1 Suppresses Liver Cancer Progression via Modulation of Epithelial–Mesenchymal Transition
por: Wang, Jianchu, et al.
Publicado: (2020)

Snail silences suppressor
por: Maxmen, Amy
Publicado: (2009)

RKIP-Mediated NF-κB Signaling is involved in ELF-MF-mediated improvement in AD rat
por: Zuo, Hongyan, et al.
Publicado: (2018)

Cefotetan-bound human RKIP involves in Ras/Raf1/MEK/ERK signaling pathway: Structural basis of the cefotetan-hRKIP interaction
por: Guo, Chenyun, et al.
Publicado: (2022)

Use of Genome-Wide Association Studies for Cancer Research and Drug Repositioning
por: Zhang, Jizhun, et al.
Publicado: (2015)

IDH1 K224 acetylation promotes colorectal cancer via miR-9-5p/NHE1 axis-mediated regulation of acidic microenvironment
por: Wang, Bo, et al.
Publicado: (2023)

TROY interacts with RKIP to promote glioma development
por: Liu, Xiujie, et al.
Publicado: (2018)

OBSERVATIONS ON SPERMIOGENESIS IN THE FUNGUS GNAT SCIARA COPROPHILA
por: Phillips, David M.
Publicado: (1966)

Handbook of the Gnats or Mosquitos, 2nd Edition
por: James, S. P.
Publicado: (1902)

Photoreceptor Structure in GNAT2-Associated Achromatopsia
por: Georgiou, Michalis, et al.
Publicado: (2020)

Urinary RKIP/p-RKIP is a potential diagnostic and prognostic marker of clear cell renal cell carcinoma
por: Papale, Massimo, et al.
Publicado: (2017)

Development and validation of a novel diagnostic model for initially clinical diagnosed gastrointestinal stromal tumors using an extreme gradient-boosting machine
por: Hu, Bozhi, et al.
Publicado: (2021)

A novel homozygous truncating GNAT1 mutation implicated in retinal degeneration
por: Carrigan, Matthew, et al.
Publicado: (2016)

Molecular Characterization and Clinical Relevance of RNA Binding Proteins in Colorectal Cancer
por: Zhang, Zhen, et al.
Publicado: (2020)

Landscape of cell heterogeneity and evolutionary trajectory in ulcerative colitis-associated colon cancer revealed by single-cell RNA sequencing
por: Wang, Quan, et al.
Publicado: (2021)

hsa_circ_0000231 Promotes colorectal cancer cell growth through upregulation of CCND2 by IGF2BP3/miR-375 dual pathway
por: Zhang, Wei, et al.
Publicado: (2022)

Correction to: Reshaping the tumour immune microenvironment in solid tumours via tumour cell and immune cell DNA methylation: from mechanisms to therapeutics
por: Zhong, Fengyun, et al.
Publicado: (2023)

Reshaping the tumour immune microenvironment in solid tumours via tumour cell and immune cell DNA methylation: from mechanisms to therapeutics
por: Zhong, Fengyun, et al.
Publicado: (2023)

Biomarkers for immune checkpoint inhibitors in colorectal cancer: recent advances and future perspectives
por: Yang, Changjiang, et al.
Publicado: (2023)

The biological complexity of RKIP signaling in human cancers
por: Farooqi, Ammad Ahmad, et al.
Publicado: (2015)

Harnessing RKIP to Combat Heart Disease and Cancer
por: Lorenz, Kristina, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_26iu5h6qjb5m6gjkrm4ulj6n6v