Lidocaine relaxation in isolated rat aortic rings is enhanced by endothelial removal: possible role of K(v), K(ATP) channels and A(2a) receptor crosstalk

BACKGROUND: Lidocaine is an approved local anesthetic and Class 1B antiarrhythmic with a number of ancillary properties. Our aim was to investigate lidocaine’s vasoreactivity properties in intact versus denuded rat thoracic aortic rings, and the effect of inhibitors of nitric oxide (NO), prostenoids...

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Detalles Bibliográficos
Autores principales: Arsyad, Aryadi, Dobson, Geoffrey P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135802/
https://www.ncbi.nlm.nih.gov/pubmed/27914476
http://dx.doi.org/10.1186/s12871-016-0286-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135802/
https://www.ncbi.nlm.nih.gov/pubmed/27914476
http://dx.doi.org/10.1186/s12871-016-0286-y

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