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Quasi-continuous parallel online scattered light, fluorescence and dissolved oxygen tension measurement combined with monitoring of the oxygen transfer rate in each well of a shaken microtiter plate

BACKGROUND: Microtiter plates (MTP) are often applied as culture vessels in high-throughput screening programs. If online measuring techniques are available, MTPs can also be applied in the first steps of process development. For such small-scale bioreactors dipping probes are usually too large; the...

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Detalles Bibliográficos
Autores principales: Ladner, Tobias, Held, Markus, Flitsch, David, Beckers, Mario, Büchs, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5135821/
https://www.ncbi.nlm.nih.gov/pubmed/27912768
http://dx.doi.org/10.1186/s12934-016-0608-2