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Targeted transplantation of mitochondria to hepatocytes

BACKGROUND: Mitochondrial defects in hepatocytes can result in liver dysfunction and death. Hepatocytes have cell-surface asialoglycoprotein receptors (AsGRs) which internalize AsGs within endosomes. The aim of this study was to determine whether mitochondria could be targeted to hepatocytes by AsGR...

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Detalles Bibliográficos
Autores principales: Gupta, Nidhi, Wu, Catherine H, Wu, George Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136362/
https://www.ncbi.nlm.nih.gov/pubmed/27942238
http://dx.doi.org/10.2147/HMER.S116852