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PTPN22 Is a Critical Regulator of Fcγ Receptor–Mediated Neutrophil Activation

Neutrophils act as a first line of defense against bacterial and fungal infections, but they are also important effectors of acute and chronic inflammation. Genome-wide association studies have established that the gene encoding the protein tyrosine phosphatase nonreceptor 22 (PTPN22) makes an impor...

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Detalles Bibliográficos
Autores principales: Vermeren, Sonja, Miles, Katherine, Chu, Julia Y., Salter, Donald, Zamoyska, Rose, Gray, Mohini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136470/
https://www.ncbi.nlm.nih.gov/pubmed/27807193
http://dx.doi.org/10.4049/jimmunol.1600604