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PTPN22 Is a Critical Regulator of Fcγ Receptor–Mediated Neutrophil Activation
Neutrophils act as a first line of defense against bacterial and fungal infections, but they are also important effectors of acute and chronic inflammation. Genome-wide association studies have established that the gene encoding the protein tyrosine phosphatase nonreceptor 22 (PTPN22) makes an impor...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136470/ https://www.ncbi.nlm.nih.gov/pubmed/27807193 http://dx.doi.org/10.4049/jimmunol.1600604 |