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The Amino-Terminal Part of the Needle-Tip Translocator LcrV of Yersinia pseudotuberculosis Is Required for Early Targeting of YopH and In vivo Virulence

Type III secretion systems (T3SS) are dedicated to targeting anti-host effector proteins into the cytosol of the host cell to promote bacterial infection. Delivery of the effectors requires three specific translocator proteins, of which the hydrophilic translocator, LcrV, is located at the tip of th...

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Detalles Bibliográficos
Autores principales: Ekestubbe, Sofie, Bröms, Jeanette E., Edgren, Tomas, Fällman, Maria, Francis, Matthew S., Forsberg, Åke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136540/
https://www.ncbi.nlm.nih.gov/pubmed/27995096
http://dx.doi.org/10.3389/fcimb.2016.00175