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Cytoplasm-Translocated Ku70/80 Complex Sensing of HBV DNA Induces Hepatitis-Associated Chemokine Secretion

Chronic hepatitis B virus (HBV) infection remains a serious disease, mainly due to its severe pathological consequences, which are difficult to cure using current therapies. When the immune system responds to hepatocytes experiencing rapid HBV replication, effector cells (such as HBV-specific CD8+ T...

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Detalles Bibliográficos
Autores principales: Li, Young, Wu, Yang, Zheng, Xiaohu, Cong, Jingjing, Liu, Yanyan, Li, Jiabin, Sun, Rui, Tian, Zhigang G., Wei, Haiming M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136554/
https://www.ncbi.nlm.nih.gov/pubmed/27994596
http://dx.doi.org/10.3389/fimmu.2016.00569