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Questions and controversies: the role of necroptosis in liver disease

Acute and chronic liver injury results in hepatocyte death and turnover. If injury becomes chronic, the continuous cell death and turnover leads to chronic inflammation, fibrosis and ultimately cirrhosis and hepatocellular carcinoma. Controlling liver cell death both in acute injury, to rescue the l...

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Detalles Bibliográficos
Autores principales: Dara, Lily, Liu, Zhang-Xu, Kaplowitz, Neil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136616/
https://www.ncbi.nlm.nih.gov/pubmed/27924226
http://dx.doi.org/10.1038/cddiscovery.2016.89