OTX2 impedes self–renewal of porcine iPS cells through downregulation of NANOG expression

The transcription factor Otx2 acts as a negative switch in the regulation of transition from naive to primed pluripotency in mouse pluripotent stem cells. However, the molecular features and function of porcine OTX2 have not been well elucidated in porcine-induced pluripotent stem cells (piPSCs). By...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Ning, Wang, Yaxian, Xie, Youlong, Wang, Huayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136617/
https://www.ncbi.nlm.nih.gov/pubmed/27924227
http://dx.doi.org/10.1038/cddiscovery.2016.90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136617/
https://www.ncbi.nlm.nih.gov/pubmed/27924227
http://dx.doi.org/10.1038/cddiscovery.2016.90

Ejemplares similares