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OTX2 impedes self–renewal of porcine iPS cells through downregulation of NANOG expression
The transcription factor Otx2 acts as a negative switch in the regulation of transition from naive to primed pluripotency in mouse pluripotent stem cells. However, the molecular features and function of porcine OTX2 have not been well elucidated in porcine-induced pluripotent stem cells (piPSCs). By...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136617/ https://www.ncbi.nlm.nih.gov/pubmed/27924227 http://dx.doi.org/10.1038/cddiscovery.2016.90 |