Dysregulated bioenergetics: a key regulator of joint inflammation

OBJECTIVES: This study examines the relationship between synovial hypoxia and cellular bioenergetics with synovial inflammation. METHODS: Primary rheumatoid arthritis synovial fibroblasts (RASF) were cultured with hypoxia, dimethyloxalylglycine (DMOG) or metabolic intermediates. Mitochondrial respir...

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Detalles Bibliográficos
Autores principales: Biniecka, M, Canavan, M, McGarry, T, Gao, W, McCormick, J, Cregan, S, Gallagher, L, Smith, T, Phelan, J J, Ryan, J, O'Sullivan, J, Ng, C T, Veale, D J, Fearon, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Basic and Translational Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136702/
https://www.ncbi.nlm.nih.gov/pubmed/27013493
http://dx.doi.org/10.1136/annrheumdis-2015-208476

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136702/
https://www.ncbi.nlm.nih.gov/pubmed/27013493
http://dx.doi.org/10.1136/annrheumdis-2015-208476

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