Helicobacter pylori vacA transcription is genetically-determined and stratifies the level of human gastric inflammation and atrophy

AIMS: Helicobacter pylori infection is the major cause of peptic ulceration and gastric cancer, and an important virulence determinant is its vacuolating cytotoxin vacA. Previously, we have described allelic variation in vacA which determines toxin activity and disease risk. Here we aimed to quantif...

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Detalles Bibliográficos
Autores principales: Sinnett, Charlotte G, Letley, Darren P, Narayanan, Geetha L, Patel, Sapna R, Hussein, Nawfal R, Zaitoun, Abed M, Robinson, Karen, Atherton, John C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136723/
https://www.ncbi.nlm.nih.gov/pubmed/27189958
http://dx.doi.org/10.1136/jclinpath-2016-203641

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136723/
https://www.ncbi.nlm.nih.gov/pubmed/27189958
http://dx.doi.org/10.1136/jclinpath-2016-203641

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