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Helicobacter pylori vacA transcription is genetically-determined and stratifies the level of human gastric inflammation and atrophy
AIMS: Helicobacter pylori infection is the major cause of peptic ulceration and gastric cancer, and an important virulence determinant is its vacuolating cytotoxin vacA. Previously, we have described allelic variation in vacA which determines toxin activity and disease risk. Here we aimed to quantif...
Autores principales: | Sinnett, Charlotte G, Letley, Darren P, Narayanan, Geetha L, Patel, Sapna R, Hussein, Nawfal R, Zaitoun, Abed M, Robinson, Karen, Atherton, John C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5136723/ https://www.ncbi.nlm.nih.gov/pubmed/27189958 http://dx.doi.org/10.1136/jclinpath-2016-203641 |
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