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Small molecules increase direct neural conversion of human fibroblasts

The generation of human induced neurons (hiNs) via exogenous delivery of neural transcription factors represents a novel technique to obtain disease and patient specific neurons. These cells have the potential to be used for disease modeling, diagnostics and drug screening, and also to be further de...

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Detalles Bibliográficos
Autores principales: Pfisterer, Ulrich, Ek, Fredrik, Lang, Stefan, Soneji, Shamit, Olsson, Roger, Parmar, Malin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137010/
https://www.ncbi.nlm.nih.gov/pubmed/27917895
http://dx.doi.org/10.1038/srep38290