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Catalytic Conversion of Lipophilic Substrates by Phase constrained Enzymes in the Aqueous or in the Membrane Phase

Both soluble and membrane-bound enzymes can catalyze the conversion of lipophilic substrates. The precise substrate access path, with regard to phase, has however, until now relied on conjecture from enzyme structural data only (certainly giving credible and valuable hypotheses). Alternative methods...

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Detalles Bibliográficos
Autores principales: Cebula, Marcus, Turan, Ilke Simsek, Sjödin, Birgitta, Thulasingam, Madhuranayaki, Brock, Joseph, Chmyrov, Volodymyr, Widengren, Jerker, Abe, Hiroshi, Mannervik, Bengt, Haeggström, Jesper Z., Rinaldo-Matthis, Agnes, Akkaya, Engin U., Morgenstern, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137027/
https://www.ncbi.nlm.nih.gov/pubmed/27917951
http://dx.doi.org/10.1038/srep38316