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RCANs regulate the convergent roles of NFATc1 in bone homeostasis

Activation of calcineurin-dependent nuclear factor of activated T cells c1 (NFATc1) is convergent for normal bone homeostasis. NFATc1 regulates both osteoclastogenesis and osteoblastogenesis. Here we investigated the roles of regulator of calcineurin (RCAN) genes in bone homeostasis. RCANs function...

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Detalles Bibliográficos
Autores principales: Kim, Jung Ha, Kim, Kabsun, Kim, Inyoung, Seong, Semun, Jeong, Byung-chul, Nam, Kwang-Il, Kim, Kyung Keun, Molkentin, Jeffery D., Kim, Nacksung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137032/
https://www.ncbi.nlm.nih.gov/pubmed/27917924
http://dx.doi.org/10.1038/srep38526