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Incomplete and delayed Sox2 deletion defines residual ear neurosensory development and maintenance

The role of Sox2 in neurosensory development is not yet fully understood. Using mice with conditional Islet1-cre mediated deletion of Sox2, we explored the function of Sox2 in neurosensory development in a model with limited cell type diversification, the inner ear. In Sox2 conditional mutants, neur...

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Detalles Bibliográficos
Autores principales: Dvorakova, Martina, Jahan, Israt, Macova, Iva, Chumak, Tetyana, Bohuslavova, Romana, Syka, Josef, Fritzsch, Bernd, Pavlinkova, Gabriela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137136/
https://www.ncbi.nlm.nih.gov/pubmed/27917898
http://dx.doi.org/10.1038/srep38253