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Chitosan-myristate nanogel as an artificial chaperone protects neuroserpin from misfolding

BACKGROUND: Molecular chaperon-like activity for protein refolding was studied using nanogel chitosan-myristic acid (CMA) and the protein neuroserpin (NS), a member of the serine proteinase inhibitor superfamily (serpin). MATERIALS AND METHODS: Recombinant his-tag fusion NS was expressed in Escheric...

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Detalles Bibliográficos
Autores principales: Nazem, Habib, Mohsenifar, Afshin, Majdi, Sahar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137230/
https://www.ncbi.nlm.nih.gov/pubmed/27995109
http://dx.doi.org/10.4103/2277-9175.190942