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TRPA1-dependent regulation of bladder detrusor smooth muscle contractility in normal and type I diabetic rats

TRPA1 is a Ca(2+)-permeable cation channel that is activated by painful low temperatures (˂17 °C), irritating chemicals, reactive metabolites and mediators of inflammation. In the bladder TRPA1 is predominantly expressed in sensory afferent nerve endings, where it mediates sensory transduction. The...

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Detalles Bibliográficos
Autores principales: Philyppov, Igor B., Paduraru, Oksana N., Gulak, Kseniya L., Skryma, Roman, Prevarskaya, Natalia, Shuba, Yaroslav M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Society of Smooth Muscle Research 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5137256/
https://www.ncbi.nlm.nih.gov/pubmed/26935999
http://dx.doi.org/10.1540/jsmr.52.1